In the three years sinceChristina Applegatewas diagnosed with multiple sclerosis, the actress medical condition has steadily progressed.

I lay in bed screaming like, the sharp pains, the ache, that squeezing, she explained.

I cant open bottles now.

Christina Applegate at the 29th Annual Screen Actors Guild Awards held at the Fairmont Century Plaza on February 26, 2023 in Los Angeles, California. (Photo by Gilbert Flores/Variety via Getty Images)

Christina Applegate at the 29th Annual Screen Actors Guild Awards on Feb. 26, 2023.Gilbert Flores/Variety/Getty Images

Kandel is the founder of Rorys Bakehouse and was diagnosed with MS in 2023.

Describing her pain, the owner said: It feels like I have knives in my stomach.

MS is an unpredictable disease that affects people differently.

Some people with MS may have only mild symptoms.